AZT: Unsafe at any Dose?

Alberta Reappraising AIDS Society

David R. Crowe, President
Phone: +1-403-289-6609
Fax: +1-403-206-7717
Email: David.Crowe@aras.ab.ca

Roger Swan, Treasurer
Box 61037, Kensington Postal Outlet
Calgary, Alberta T2N 4S6
Canada
Office
Phone: +1-403-220-0129
Email: aras@aras.ab.ca
Web: noaids.ca

AZT: Unsafe at any Dose?

AZT and Mitochondria

Mitochondria are the energy regulating organelles in every living cell. Because they are self-replicating and therefore have their own DNA they are susceptible to damage from drugs (such as AZT) that interfere with DNA replication (mitosis). In fact, they are more susceptible, because they don't have the same repair mechanisms as the DNA in the cell's nucleus. Symptoms of mitochondrial damage are varied, but often include muscle damage, as the ability of the cells to obtain energy is diminished.

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© Copyright November 2017: Alberta Reappraising AIDS Society